Estradiol LabCorp

Estradiol is the predominant sex hormone present in females and is also found in lower levels in men. Estradiol is one of three estrogens, the other two being estrone and estriol. Estradiol represents the major estrogen in humans. Estradiol not only impacts reproductive and sexual functioning; but also affects other systems including bone health, heart health, nerves, and metabolism. Estradiol (also known as E2) is the most active of all three estrogens commonly measured in a clinical setting. In women, it is important to compare the relationship between Estradiol and Progesterone in the evaluation of menopausal symptoms such as hot flashes, mood disorders, and aging skin. In men, high levels of estradiol are associated with abdominal fat, enlargement of the prostate, and cardiovascular risk. In both men and women, low levels of estradiol are associated with osteoporosis. Estrogen is important to monitor in men also, but it is important to order the SENSITIVE Estradiol (E2) test for men, as it is a more accurate way to test Estradiol in males. Since it is important to check estradiol in relationship to other hormones, we recommend having the Comprehensive Hormone and Wellness Panel for Men and/or Women completed.